Evidence Based Practice

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The Benefits of Platelet- Rich Fibrin

A NEW FRONT IN MEDICAL THERAPIES Wound healing and tissue regeneration are fundamental goals of medical care. In this context, the use of autologous blood concentrates has emerged. Historically, the primary use of such therapy was in oral maxillofacial surgery;1 however, its use in surgical and noninvasive esthetic procedures has shown notable success, suggesting a bright future for esthetic and reconstructive medicine. Autologous platelet therapy gained popularity in the 1990s with the use of platelet-rich plasma (PRP), which has since found several medical applications. The focus of this article is the next generation of autologous blood concentrate therapy, platelet-rich fibrin (PRF), and its roles in esthetic medicine. The significance of these developments will become apparent throughout the review of the composition of whole blood.